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Vânia André Assistant Researcher at CQE-IST and IMS |
As a chemical engineer with a passion for chemistry research, I have gradually taken on the role of an independent researcher in solid state chemistry. My journey in research began in 1999, during the first year of my Chemical Engineering degree, when I joined the project "On the Rocks." In this project, I studied the impact of various rocks on the growth and crystal structure of inorganic crystals.
In 2006, my interest in crystals led me to delve into the emerging field of crystal engineering and supramolecular chemistry. I further explored this field in my Master's and PhD projects, which involved the design of new crystal forms of active pharmaceutical ingredients. Additionally, I have studied metallodrugs and metallopharmaceuticals, where I discovered that mechanochemistry is a highly effective synthetic technique.
Since 2012, I have been focused on developing BioMOFs, metal organic frameworks with potential pharmacological applications in controlled drug delivery. Currently, I am applying my expertise to rejuvenate old antibiotics using crystal engineering and supramolecular chemistry strategies, with the goal of finding more efficient methods for fighting multi-resistant microorganisms. To this end, I served as the Principal Investigator of the Project LISBOA-01-0145-FEDER-030988 (PTDC/QUI-OUT/30988/2017), which aimed to enhance the bioactivity of drugs through antibiotic coordination frameworks.
My expertise in mechanochemistry has also led to my participation in the COST Action MechSustInd and the European Project IMPACTIVE.
Over the years, I have gained expertise in crystallography through the use of X-ray diffraction techniques, both in single crystal and powder form. Recently, I had the opportunity to collect data at the ESRF, the most powerful synchrotron radiation source in Europe. I am also familiar with other characterization techniques such as differential scanning calorimetry, thermogravimetric analysis, hot-stage microscopy, and infrared spectroscopy.
Organizationally, I have been a member of the organizing committee of several national and international conferences, including the National Training Site Modern Methods of Structure Elucidation, held at CQE, IST (2009-present), and was a member of the organization committee for the 48th Crystallographic Course at the Ettore Majorana Centre in Italy (June 2015). Furthermore, I served as the Portuguese Representative for the General Interest Group for Young Crystallographers of the European Crystallographic Association (2011-2016).
In 2006, my interest in crystals led me to delve into the emerging field of crystal engineering and supramolecular chemistry. I further explored this field in my Master's and PhD projects, which involved the design of new crystal forms of active pharmaceutical ingredients. Additionally, I have studied metallodrugs and metallopharmaceuticals, where I discovered that mechanochemistry is a highly effective synthetic technique.
Since 2012, I have been focused on developing BioMOFs, metal organic frameworks with potential pharmacological applications in controlled drug delivery. Currently, I am applying my expertise to rejuvenate old antibiotics using crystal engineering and supramolecular chemistry strategies, with the goal of finding more efficient methods for fighting multi-resistant microorganisms. To this end, I served as the Principal Investigator of the Project LISBOA-01-0145-FEDER-030988 (PTDC/QUI-OUT/30988/2017), which aimed to enhance the bioactivity of drugs through antibiotic coordination frameworks.
My expertise in mechanochemistry has also led to my participation in the COST Action MechSustInd and the European Project IMPACTIVE.
Over the years, I have gained expertise in crystallography through the use of X-ray diffraction techniques, both in single crystal and powder form. Recently, I had the opportunity to collect data at the ESRF, the most powerful synchrotron radiation source in Europe. I am also familiar with other characterization techniques such as differential scanning calorimetry, thermogravimetric analysis, hot-stage microscopy, and infrared spectroscopy.
Organizationally, I have been a member of the organizing committee of several national and international conferences, including the National Training Site Modern Methods of Structure Elucidation, held at CQE, IST (2009-present), and was a member of the organization committee for the 48th Crystallographic Course at the Ettore Majorana Centre in Italy (June 2015). Furthermore, I served as the Portuguese Representative for the General Interest Group for Young Crystallographers of the European Crystallographic Association (2011-2016).
